Conclusion: Parapsoriasis and Psoriasis Similarities and Differences

"Para" is a prefix meaning beside, behind, accessory to, apart from, etc.

Parapsoriasis does have similarity to psoriasis, but in reality these are 2 different diseases.

1. Parapsoriasis may sometimes transform into a Cutaneous T-cell Lymphoma - a type of cancer of the immune system, and psoriasis - never.

2. Para psoriasis lesions are much redder, and sometimes even cyan, yellow or light brown, unlike psoriasis, which is pink with silvery plaques.

3. Parapsoriasis involves only the skin; psoriasis can involve the nails (Nail Psoriasis) and joints (Psoriatic Arthritis).

4. In both psoriasis and parapsoriasis the T cells act abnormally; however, with parapsoriasis they mutate, and with psoriasis they are simply overactive.

5. The appearance of parapsoriasis lesions may be accompanied with burning and pain, and psoriasis lesions - only with an itch.

6. Para psoriasis usually is not accompanied by an itch, unlike psoriasis.

7. Parapsoriasis may leave slightly lowered scars, and psoriasis never leaves any scars on the skin.

8. Similar to psoriasis, parapsoriasis can be treated by UVB and topical steroids, but unlike psoriasis - also by antibiotics.

9. Para psoriasis may be triggered by infectious and bacterial diseases and vaccinations, which is similar to guttate psoriasis.

Skin biopsy is the most prudent thing to do if a diagnosis points to both - psoriasis or parapsoriasis.

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