|
Uric Acid May Extend the Lifespan
Antioxidants defend the body against the damage from free radicals.
The body is constantly trying to balance oxidative stress with antioxidants.
Antioxidants protect other body cells (lipids, proteins, DNA) against the damage from free radicals by converting the free radicals into harmless molecules.
The body on its own makes antioxidants like Uric Acid, coenzyme Q-10 and others. Other antioxidants are found in our diet, like vitamins C, E etc.
Various studies suggest that Uric Acid may be one of the major natural antioxidants of the body.
An increased reactive oxygen species (ROS) and a lowered antioxidant activity have been determined in the psoriatic plaques.
A question: is antioxidant protection lowered in the whole body of the people with psoriasis?
Answer is: people with psoriasis, on the contrary, have an increased antioxidant protection in the rest of their body, with the exception of their psoriatic plaques.
To prove this there was conducted a study, which measured the most well-known antioxidants in the serum of 33 patients with severe psoriasis and in 36 control persons without psoriasis.
In the people with psoriasis several antioxidants (tocopherol and bilirubin) were increased, but only slightly; but an antioxidant Uric Acid was increased by a whole 33% compared to the controls without psoriasis.
Other parameters such as total protein and thiol content and ascorbic acid did not differ from controls.
High levels of Uric Acid can prevent the oxidative stress, connected with the aging, thus extending the lifespan of a human (Ames BN, Cathcart R, Schwiers E, Hochstein P. Uric Acid provides an antioxidant defense in humans against oxidant- and radical-caused aging and cancer: a hypothesis. Proc Natl Acad Sci USA 1981;78:6858-62.).
CONCLUSION 5:
High levels of Uric Acid may cause an extension of the lifespan of the people with psoriasis, compared to the people without psoriasis.
Therefore the people with psoriasis may live longer than the people without psoriasis.
For all of the above, people with psoriasis often pay with their psoriatic plaques.
Exceptions compose the people with the so-called "concealed psoriasis" - i.e. no visual psoriasis manifestations, and with only the internal deviations. Such people may be the really lucky ones - i.e., they may possess all of the above benefits with no disadvantages of having psoriasis on the skin or joints in the case of a psoriatic arthritis.
Thank you for reading and:
PLEASE SPREAD the WORD if You Find This Information Valuable for the Other Psoriasis Sufferers!
 |
